Chromosome abnormality

  • the three major single-chromosome mutations: deletion (1), duplication (2) and inversion (3).
    the two major two-chromosome mutations: insertion (1) and translocation (2).

    a chromosomal disorder, anomaly, aberration, or mutation is a missing, extra, or irregular portion of chromosomal dna.[1] it can be from a typical number of chromosomes or a structural abnormality in one or more chromosomes. chromosome mutation was formerly used in a strict sense to mean a change in a chromosomal segment, involving more than one gene.[2] the term "karyotype" refers to the full set of chromosomes from an individual; this can be compared to a "normal" karyotype for the species via genetic testing. a chromosome anomaly may be detected or confirmed in this manner. chromosome anomalies usually occur when there is an error in cell division following meiosis or mitosis. there are many types of chromosome anomalies. they can be organized into two basic groups, numerical and structural anomalies.

  • numerical disorders
  • structural abnormalities
  • inheritance
  • acquired chromosome abnormalities
  • dna damage during spermatogenesis
  • detection
  • see also
  • references
  • external links

The three major single-chromosome mutations: deletion (1), duplication (2) and inversion (3).
The two major two-chromosome mutations: insertion (1) and Translocation (2).

A chromosomal disorder, anomaly, aberration, or mutation is a missing, extra, or irregular portion of chromosomal DNA.[1] It can be from a typical number of chromosomes or a structural abnormality in one or more chromosomes. Chromosome mutation was formerly used in a strict sense to mean a change in a chromosomal segment, involving more than one gene.[2] The term "karyotype" refers to the full set of chromosomes from an individual; this can be compared to a "normal" karyotype for the species via genetic testing. A chromosome anomaly may be detected or confirmed in this manner. Chromosome anomalies usually occur when there is an error in cell division following meiosis or mitosis. There are many types of chromosome anomalies. They can be organized into two basic groups, numerical and structural anomalies.